http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2298867-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d17ff54f3706245b8e25f8b0d22316cf |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-96433 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-177 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6467 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate | 1998-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e85937177383c336b0d7b51f3da5140 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_371182d3d709d0d38004eaa4c7915ac4 |
publicationDate | 1999-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2298867-A1 |
titleOfInvention | Methods for using granzymes and binding molecules thereof for treating diseases characterized by abnormal apoptosis |
abstract | A method for determining if an animal is at risk for a disease resulting in abnormal apoptosis is described. An animal is provided and an aspect of metabolism or structure of a serine protease, e.g., a granzyme, or a serine protease binding molecule in the animal is evaluated. An abnormality in the aspect of the metabolism or structure is diagnostic of being at risk for a disease resulting in abnormal apoptosis. Also described are methods for evaluating an agent for use in modulating apoptosis, methods for effecting or inhibiting apoptosis in a cell, and methods for treating unwanted cell or infectious particle proliferation or treating an autoimmune disease or a transplant graft rejection in an animal. Pharmaceutical compositions are also provided. |
priorityDate | 1997-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 203.