| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_087bed7abab91ae0f927879f9fe8b273 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-805 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-805
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 |
| filingDate |
1998-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf1b2c22a8d390cd06ed477835b2745a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d1ff254c6489fbb57d2574364a68fa7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e72c48727d2a27161625bbaa28d8f0e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb503df3b9e4a05bef2ba2d604d94577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48768a3bf74303fbe9705791ecaa5f51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_860d6f517d59a0e58b231e96cf8104c0 |
| publicationDate |
1999-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2297362-A1 |
| titleOfInvention |
Methods of unfolding proteins using metal complexes |
| abstract |
The invention relates to methods of unfolding proteins using metal complexes, particularly cobalt-containing Schiff's base compounds. The proteins can be viral proteins or myoglobin, and the unfolding can be irreversible under physiological conditions. The unfolded proteins exhibit UV/vis absorption spectral changes (see the figure) and a 5 % or greater change in at least one minima or maxima of the circular dichroism spectra of the proteins. |
| priorityDate |
1997-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |