http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2297361-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1dfd39878009ed672c93ba0247ee666 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-10 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6887 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate | 2000-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93931ccb98231099d662f8d4134e576c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ba5fb40d96d8790fd8cc43448227d15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecfd3e1dfcf711953113ee2a87340d21 |
publicationDate | 2001-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2297361-A1 |
titleOfInvention | Methods of diagnosing muscle damage |
abstract | A method for assessing muscle damage in a biological sample obtained from a subject is disclosed. The method involves obtaining a biological sample from a subject being assessed for muscle damage, and evaluating the sample for the presence or absence of a myofilament protein modification product. Preferably, the myofilament protein modification product is a chemical adduct of a myofilament protein. The method can also be used to assess the extent and/or type of muscle damage in a subject by studying the profile of myofilament protein modification products detected in the sample taken from the subject. The invention further provides a method for screening for an agent which modulates the level of a myofilament protein modification product present in a biological sample or for a calcium sensitizing agent. The invention is applicable to cardiac muscle and skeletal muscle. |
priorityDate | 1999-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5460341 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419559505 |
Total number of triples: 17.