http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2294179-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5143286a65393c4b5ab5ffe8cfc76422 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-975 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-90245 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 |
| filingDate | 1998-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9d4ed5208f76475c9a4d7f13123f4c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d3329828e7455aedaaa5b4c5ef8d105 |
| publicationDate | 1998-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2294179-A1 |
| titleOfInvention | Diagnostic methods and kits for the evaluation of the sympathetic nervous system function |
| abstract | The present invention relates to an in vitro diagnostic method for the determination of specific dopamine-.beta.-hydroxylase activity for the evaluation of the sympathetic nervous system function of a patient from a serum sample; which comprises the steps of: a) filtering the serum sample to substantially remove drugs and endogenous inhibitors of dopamine-.beta.-hydroxylase; b) incubating the filtered sample of step a) with a substrate of dopamine-.beta.-hydroxylase for conversion in a detectable compound; c) determining the amount of detectable compound to evaluate dopamine-.beta.-hydroxylase activity and comparing with a normal sample; whereby an amount lower than a normal sample is indicative of a reduced sympathetic nervous system function and an amount higher than a normal sample is indicative of an increased sympathetic nervous system function. A reduction in the sympathetic nervous system function is indicative of neurodegenerative, neuroendocrine, psycho-affective and cardiovascular diseases, burn-out, and chronic fatigue, and the effects of stress such as panic syndrome. An increase in the sympathetic nervous system function is indicative of the effects of stress. |
| priorityDate | 1997-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 175.