| abstract |
The invention provides a process for the production of a 2,3dihydroxypropylamino compound, said process comprising the reaction steps of: (i) obtaining an allylamino compound; (ii) epoxidizing said allylamino compound to yield an epoxypropylamino compound; and (iii) hydrolysing said epoxypropylamino compound to yield a 2,3-dihydroxypropylamino compound. This process may be used to produce simple 2,3-dihydroxypropylamino compounds such as APD or complex ones such as BAPD (an intermediate in the production of iohexol). |