http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2275566-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dbe1d40faa1ed62003e4b49d8b278688 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 |
| filingDate | 1998-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24e407ab32199d69bcd95a289cddde09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17f178522977c844272207dc0ad75ac1 |
| publicationDate | 1998-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2275566-A1 |
| titleOfInvention | 2,4-diaminopyrimidine compounds as anti-cancer agents |
| abstract | Use of a compound of general formula (I) wherein R1 and R2 are independently selected amino groups; R3 is C1-6 alkyl or haloalkyl; R4 is selected from alkoxy, aralkoxy, haloalkyl, halogen and amino; and R5 is selected from nitro, amino, azido or a group -N=X-NR6R7 where R6 and R7 are independently C1-6 alkyl or are aralkyl or together with the nitrogen to which they are attached form a heterocyclic ring with the proviso that one or both R6 and R7 or the heterocyclic ring carries or includes or carries and includes at least one oxygen or sulphur atom, and X is N or CH or CR9; or R4 and R5 together with the benzene ring to which they are attached form a group of formula (II), wherein X is N, CH or CR9, and R8 is C1-6 alkyl or is aralkyl; or R4 and R5 together with the benzene ring to which they are attached form a group of formula (III) wherein R9 is aryl or aralkyl; or a salt or N-oxide of any such compound, for the manufacture of a medicament for the treatment of mutant-ras gene associated cancer. |
| priorityDate | 1997-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.