http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2275353-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116c851e729089df9a427027272fa290 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-70 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate | 1997-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f81145c22a29ea9ff06e46a8fa70e763 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13cef998400c3df5a35c6c2b6883e6a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_651cf987250fd1cacb236725ee9c19ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3769c4483a2dd4a31782aa899cb9430 |
| publicationDate | 2007-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2275353-C |
| titleOfInvention | 1-phenylalkyl-1,2,3,6-tetrahydropyridines for treating alzheimer's disease |
| abstract | The invention concern compounds of formula (I) in which Y represents -CH- or -N-; R1 represents hydrogen, a halogen, a CF3 group, (C1-C4)alkyl or (C1-C4)alcoxyl; R2 represents a methyl or ethyl group; R3 and R4 each represent hydrogen or a (C1-C3)alkyl; X represents (a) a (C1-C6)alkyl; a (C1-C6)alcoxyl; a (C3-C7)carboxyalkyl; a (C1-C4)alcoxycarbonyl(C1-C6)alkyl; a (C3-C7)carboxyalcoxyl; or a (C1-C4)alcoxycarbonyl(C1-C6)alcoxyl; (b) a radical selected among a(C3-C7)cycloalkyl, (C3-C7)cycloalkyloxy, (C3-C7)cycloalkylmethyl, (C3-C7)cycloalkylamino and cyclohexenyl, said radical can be substituted by a halogen, hydroxy, (C1-C4)alcoxy, carboxy, (C1-C4)alcoxycarbonyl, amino, mono-or di-(C1-C4) alkylamino; or (c) a group selected among a phenyl, phenoxy, phenylamino, N-(C1-C3)alkylphenylamino, phenylmethyl, phenylethyl, phenylcarbonyl, phenylthio, phenylsuphonyl, phenylsulphinyl or styryl, said group can be mono- or poly-substituted by a halogen, CF3, (C1-C4)alkyl, (C1-C4)alcoxy, cyano, amino, mono- or di-(C1-C4)alkylamino, (C1-C4)acylamino, carboxy, (C1-C4)alcoxycarbonyl, aminocarbonyl, mono- or di-(C1-C4)alkylaminocarbonyl, amino(C1-C4)alkyl, hydroxy(C1-C4)alkyl or halogeno(C1-C4)alkyl. The invention also concerns a method for preparing them and the pharmaceutical compositions containing them. These compounds have a neurotrophic and neuroprotecting activity. |
| priorityDate | 1996-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 258.