http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2273959-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-117497 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B23-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B23-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-06 |
| filingDate | 1997-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89ed8709ca2f120201d4f368850f89f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19cbf9f51a4f9fbd39f5c3b60a451579 |
| publicationDate | 1998-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2273959-A1 |
| titleOfInvention | Helium-neon excitable reticulocyte dyes derivable from halolepidines |
| abstract | A method for synthesizing dyes excitable by a helium-neon laser (excitable at 633 nm) from halolepidines, e.g., 7-halolepidine, which dyes are suitable for the detection and enumeration of reticulocytes in human blood samples. In another aspect, this invention provides a method for immunotyping phenocytes. The method is based on the phenomenon that when dyes of certain structure intercalate into DNA or RNA, the intensity of the dyes increases. Dyes suitable for this invention can be described as having: (a) a first heterocyclic moiety, (b) a second heterocyclic moiety, and (c) a linking group that connects the first and second heterocyclic moieties. Both the first and second heterocyclic moieties must contain at least two rings, preferably fused together. The dye is characterized by conjugation whereby the first moiety is ethylenically conjugated to the second moiety. The general structure of dyes suitable for use in this invention is shown in formula (I) wherein R1, R2, R3, R4 independently represent a member selected from the group consisting of hydrogen, halogen, cyano, alkyl, aryl, alkaryl, aralkyl, or R1 and R2 taken together, or R2 and R3 taken together, or R3 and R4 taken together represent one or more rings; R5 represents an alkyl group or an aryl group; R6, R7, R8, R9 independently represent a member selected from the group consisting of hydrogen, halogen, cyano, alkyl, aryl, alkaryl, aralkyl, or R6 and R7 taken together, or R7 and R8 taken together, or R8 and R9 taken together represent one or more rings, provided that at least one of R6, R7, R8, R9 represents halogen; R10 represents an alkyl group or an aryl group; R11, R12 independently represent a member selected from the group consisting of hydrogen, halogen, cyano, alkyl, aryl, alkaryl, aralkyl, or R11 and R12 taken together represent one or more rings; R13 represents hydrogen or an alkyl group; Y represents S, O, C, or Se, provided that Y is not N; and n represents a number from 0 to 3. |
| priorityDate | 1996-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID454973655 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458392451 |
Total number of triples: 25.