| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12C11-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-41 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B41-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-43 |
| filingDate |
1999-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65ea0cb204d9f1960b3802143a06c29d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_424ddd162e5fde7ba527cc6d11e56338
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f380f6c83dc0a2a3a9b943fcd5d8012 |
| publicationDate |
1999-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2273643-A1 |
| titleOfInvention |
Stereoselective reduction of carbonyl compounds |
| abstract |
A process for the stereoselective reduction via a Meerwein-Ponndorf-Verley (MPV) reaction, of a carbonyl compound to the corresponding alcohol. A preferred starting carbonyl compound is a ketone compound wherein the carbonyl carbon is prochiral. The starting carbonyl compound is contacted with an MPV mediator such as aluminum isopropoxide. The reaction is conducted under mild conditions, e.g. temperatures of about 50°C or less, for less than four hours, and is capable of producing an excess (about 90% to about 97% or more) of a desired optically active chiral alcohol. The mild reaction conditions preserve the optical orientation of other asymmetric centers in the carbonyl compound starting material. Steroselective and stereospecific reactions for producing desired optically active alcohols are useful for the preparation of intermediate and final pharmaceutical products. |
| priorityDate |
1998-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |