abstract |
A stabilized enzyme formulation is disclosed which comprises phytase and at least one stabilizing agent selected from the group consisting of: a) C5 sugars such as xylitol and ribitol, b) polyethylene glycol having a molecular weight of 600 to 4000 Da, c) the disodium salts of malonic, succinic and glutaric acid, and d) carboxymethylcellulose, and e) sodium alginate. Alternatively, phytase may be stabilized by chemical crosslinking with either a) glutaraldehyde, or b) oxidation of phytase carbohydrate residues with sodium periodate and subsequent addition of adipic acid dihydrazide. |