| abstract |
The invention relates to new histidine derivatives corresponding to the formula general (I) below: in which n is not an integer going from 0 to 5, n is an integer ranging from 1 to 16, R represents a side chain of an amino acid, X represents a radical chosen from the radicals of formulas, read from the left at right: -NH-CO-, -SO2-, -NH-CO-CO-, -O-CO-CO-, R 'represents a linear or branched, saturated or unsaturated alkyl radical, optionally hydroxylated, C6 to C22 or an aminoalkyl radical C6 to C22, function amine being optionally protected in the form of acetamide or substituted by a or two lower alkyl groups, Q + represents H + or an organic or inorganic cation, as well as the addition salts of a compound of formula (I) with an acid organic or mineral, The invention relates equally to compounds with configuration D, with L configuration as their mixtures, especially the racemic mixture of compounds D and L. The invention also relates to a process for preparing the compounds of formula (I) as well as the use of these compounds in cosmetics and pharmacy. |