| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a5c90c8948d48ed7f60962f1b2d2b2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-4405
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-448
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-30153
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-30677
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2310-00293
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-30261
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-30133
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2230-0069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B17-7062
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2230-0082
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2230-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2230-0015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2002-30224
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-442 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-447
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-4465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-146
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-425
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-446
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B17-707 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B17-70 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-44 |
| filingDate |
1997-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_300bcd5dd21294cf87c06bccb59e5beb |
| publicationDate |
1998-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2269254-A1 |
| titleOfInvention |
Ceramic fusion implants and compositions containing osteoinductive factors |
| abstract |
Bone graft substitute compositions are provided for promoting new bone growth and arthrodesis. The compositions include a carrier for controlled delivery of osteoinductive factors. In one embodiment, the carriers include a biphasic calcium phosphate ceramic having between about 2-40 % hydroxyapatite and about 98-60 % tricalcium phosphate by volume, and a calcium/phosphorous ratio of between about 1.50 to about 1.60. The invention also includes osteoinductive compositions including the carriers and an effective amount of a bone morphogenetic protein dispersed within the ceramic. The composition has a weight ratio of protein to ceramic of no more than about 1:200. In a specific embodiment, the weight ratio of protein to ceramic is between about 1:200 and about 1:2000. Spinal implants (10) are also provided which include a body (11) having a wall (12) sized for engagement within a space (S) between adjacent vertebrae (V) to maintain the space (S) and a confining matrix (13) for confining new bone growth to the body (11). |
| priorityDate |
1996-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |