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filingDate 1999-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ddc93bca52bb5bf803c39feb0d14582
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publicationDate 1999-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2269109-A1
titleOfInvention Protease for activating clotting factor vii
abstract A protease for activating the blood clotting factor VII and its proenzyme is described. Moreover, a process for obtaining the protease and its use in hemorrhage prophylaxis or hemostasis is described. A stabilized factor V and a stabilized factor VIII preparation are furthermore described which are free of the inactive factor VIII fragments formed by proteolytic degradation as a result of the inhibition or the removal of the protease activating the blood clotting factor VII. Moreover, a test system for the qualitative and quantitative detection of a protease which activates the blood clotting factor VII is described. Finally, pharmaceutical preparations are described which are suitable for the prophylaxis and treatment of bleeding events, e.g. in the presence of FVIII inhibitors, wound healing and for the treatment of disorders which are caused by fibrin-containing thrombin. The preparations contain the protease activating the blood clotting factor 'VII, or its proenzyme.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7202065-B2
priorityDate 1998-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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