| abstract |
A process for the preparation of a substituted aromatic compound in which a chloroaromatic compound and an alkyl-, alkenyl- or aryl-boronic acid, ester or anhydride are coupled in the presence of palladium and a lipophilic aliphatic phosphine comprising at least one branched aliphatic group or a lipophilic aliphatic bis(phosphine). Preferred phosphines include triisopropyl, triisobutyl and tricyclohexylphosphine. |