| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1647
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-683
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B02C23-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-382 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-382
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B02C23-06 |
| filingDate |
1997-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c01d7cf5a0b9be6ac042cc9527be61d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4204e7e1f8f58bae10c11804a2583412
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f5f00f8434264a9b79da450c8147da4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_889eb20d215062194c3cef5a5d28a639 |
| publicationDate |
1998-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2267930-A1 |
| titleOfInvention |
A method for producing a microparticle |
| abstract |
This invention provides a method for producing a microparticle which comprises pulverizing a solid preparation comprising a compound represented by formula (I), wherein ring A is an optionally substituted benzene ring; R is a hydrogen atom or an optionally substituted hydrocarbon group; B is an optionally esterified or amidated carboxyl group; X is -CH(OH)- or -CO-; k is 0 or 1; and n is 0, 1 or 2 or a pharmaceutically acceptable salt thereof and a biodegradable polymer of .alpha.-hydroxycarboxylic acid in the presence of a pulverizing auxiliary, which can provide microparticles which are less adhesive and involve less aggregation and are thus excellent in drug entrapment ratio and control of drug release in a desired particle size. |
| priorityDate |
1996-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |