| abstract |
Novel 1-(biphenyl-4-yl)methyl-1H-1,2,4-triazoles and 1-(biphenyl-4-yl)methyl-4H-1,2,4-triazoles each having a (2,4-dioxopyrrolidine-5-ylidene)methyl or (2,4-dioxotetrahydrofuran-5-ylidene)methyl group as the substituent at the 2'-position, salts thereof, and medicines containing these compounds as the active ingredient. These compounds are lowly toxic and highly safe and are useful as an angiotensin II antagonist. |