| abstract |
The invention solves a method of preparation of omeprazole by a reaction of 5methoxy-2-ยข(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio!-1H-benzimidazole with peroxyacetic acid in a two-phase water and chlorinated organic solvent medium, in alkaline pH, subsequent separation of water and organic phases after the reaction and isolation of omeprazole from organic phase. |