Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cbffa3b81b3b862dc7220b5648f5f745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26c1d408efa35ae2434000bb0b44f24d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-23 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43563 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4723 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate |
1998-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2002-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eafa83da0e3c581291a131dfe9795a64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df3f88afff0967000cb5cf32784b43ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b6f0899828e9799608373b22945ed65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1906edcf93c3f5ba1cd006e9f4734c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c527b6a5852ec5886309b30b181673f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a77e5436346a975ba9b4b84e909ab887 |
publicationDate |
2002-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2261569-C |
titleOfInvention |
Method for mass production of antimicrobial peptide |
abstract |
The present invention provides a method for mass production of an antimicrobial peptide, which comprises the steps of: constructing a fusion gene containing a first gene encoding a negatively charged acidic peptide having at least two cysteine residues and a second gene encoding a positively charged basic antimicrobial peptide; transforming a host microorganism with an expression vector comprising the fusion gene; cultivating the transformed microorganism to express a fusion peptide containing the acidic peptide and the antimicrobial peptide; and, recovering the expressed antimicrobial peptide. In accordance with the present invention, the inhibitory effect of the expressed antimicrobial peptide on the growth of host microorganism can be dramatically minimized by fusing it with the acidic peptide. Accordingly, antimicrobial peptides can be produced massively from a recombinant microorganism regardless of the kind of the antimicrobial peptides. |
priorityDate |
1997-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |