| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef673e5306c467eaa60d4b5260c05da1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2613944636ab2fdf3f83ef2d4b304f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f4cc6389f861694c0b2d2d95a848798
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_11b7010966c1b14cef586cbb04d6be0d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f82a9977c4199f0a0652f42d889c8375 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2845
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-34 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate |
1996-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ed262938c801dea7c82eb7f8301185d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c62ff39d0910e9940b9ece74287f4b63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_277369229cb7d30f39099d6fad2cadea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5ad9518ccb61937ed18d4ea8425e0ee |
| publicationDate |
1997-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2260808-A1 |
| titleOfInvention |
Method of restoring a functional protein in a tissue by cell transplantation |
| abstract |
The present invention relates to a method for improving the success of a transplantation which at least addresses to one of the most serious problems: transplant survival. The method comprises the steps of transplanting donor cells in a patient in need for such a transplantation, the transplantation being made in the presence of an agent blocking the interaction between a ICAM-1 molecule located at the membrane surface of the donor cell and a LFA-1 molecule located at the membrane surface of the patient's leucocytes, which blocking increases the viability of said transplanted donor cells by at least about four fold. The agent blocking this interaction is an anti-LFA-1 antibody which is injected to the host at the time of transplantation or an anti-ICAM-1 antibody fragment which is not capable of fixing complement, such as a F(ab)2 fragment. |
| priorityDate |
1996-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |