| abstract |
The DNAs of the invention are characterized in that they are all or part of genes, with their reading phase, present in Neisseria meningitidis, but absent either in Neisseria gonorrhoeae or in Neisseria lactamica with the exception of genes involved in the biosynthesis of the polysaccharide capsule, frpA, frpC, opc, porA, rotamase, of the sequence IC1106, IgA proteases, pillin, pilC, proteins which bind transferrin and opacity proteins. The invention also relates to the polypeptides corresponding to these DNAs and the antibodies directed against these polypeptides. Applications to the prevention and detection of meningococcal infections and meningitis. |