http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2256357-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3507a2e70f62cc6dea31d79e161e0380 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-02 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-02 |
| filingDate | 1997-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29ee9551695f6617daaf6465db57a57f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f00e2cc1e62e4e69db687dadefd0da2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e93756ad78ce6bcc1404859c647f5e07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2809bb07cc3dfb62f175f1dcefaf7df0 |
| publicationDate | 2008-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2256357-C |
| titleOfInvention | Enhanced production of taxanes by cell cultures of taxus species |
| abstract | This invention provides methods whereby taxol, baccatin III, and other taxol - like compounds, or taxanes, can be produced in very high yield from all known Taxus species, e.g., brevifolia, canadensis, cuspidata, baccata, globosa, floridana, wallichiana, media and chinensis. Particular modifications of culture conditions (i.e., media composition and operating modes) have been discovered to enhance the yield of various taxanes from cell culture of all species of Taxus. Particularly preferred enhancement agents include silver ion or complex, jasmonic acid (especially the methyl ester), auxin-related growth regulators, and inhibitors of the phenylpropanoid pathway, such as 3,4-methylenedioxy-6-nitrocinnamic acid. These enhancement agents may be used alone or in combination with one another or other yield-enhancing conditions. While the yield of taxanes from plant cell cultu re of T. chinensis is particularly enhanced by use of one or more of these conditions, yield of taxanes for all Taxus species has been found to benefit from use of these conditions. |
| priorityDate | 1996-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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