| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8859c1c91fc9a4c625f9a8c07d970582
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a1b4b4b21b425a0f495ecb47c7e27385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ad3c0badb206ebb25673e612a0b3b73 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-281 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-483 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-483
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-055 |
| filingDate |
1998-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2008-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cf687a901b257413efc7a5139f3f816
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c86e6f37778c0d15c661240adefed19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44df36bafa345bca8b5a7dd8f3d9cb9e |
| publicationDate |
2008-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2254952-C |
| titleOfInvention |
Method of evaluating the efficacy of drug on brain nerve cells |
| abstract |
The present invention relates to a method to measure in vivo the effect of a drug on the function of the nerve cells of the brain of a patient suffering from a neurological disease, which comprises the steps of: a) measuring NAA signal intensity using MRS of the brain of the patient; b) subjecting the patient to a treatment with the drug to be tested and measuring NAA signal intensity using MRS of the brain of the patient; and c) comparing the spectra of steps a) and b) to determine whether the drug has an effect on the function of the nerve cells of the brain; whereby the increase in the NAA signal of step b) is indicative of a drug with a positive effect. |
| priorityDate |
1997-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |