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filingDate 1997-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_400ee94c5ddfc9e9374b12e0889d602d
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publicationDate 1997-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2253737-A1
titleOfInvention Micellar aqueous composition and method for solubilizing hydrophobic drug
abstract A micellar aqueous composition which comprises a chitosan derivative having carboxy (C1-5)alkyl groups as a hydrophilic group and C9-21 alkyl or aliphatic C9-21 acyl groups as a hydrophobic group introduced thereinto and a hydrophobic drug; and a method for solubilizing a hydrophobic drug which comprises adding the above-mentioned chitosan derivative together with the hydrophobic drug to an aqueous solvent to thereby form a micellar aqueous composition. Thus, drugs which are insoluble in water and, therefore, can hardly be injected by the conventional methods can be processed into injections. Moreover, it is expected that a sorbefacient effect can be exerted on drugs which have poor solubility in preparations for oral administration, etc.
priorityDate 1996-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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