| abstract |
Disclosed are novel compounds of the formula: (see formula I) (wherein R1 is optionally substituted phenyl or pyridyl; R2 is phenyl or 5- or 6-membered heteroaryl; and R3 is H, halo, CN, NO2, CF3, alkyl or alkoxy) which are .alpha.-amino-3-hydroxy-5- methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist and are useful as medicine for treating neurodegenerative and CNS-trauma related conditions. |