http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2250067-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9e4cedb72851f01dadac14d585e8b17 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 |
| filingDate | 1997-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a9440aba1b4a70d54ee66457e77d5ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09cca6d825c34750f9ca7e088ed1d7fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_296264062c425a15c4897087b54ed619 |
| publicationDate | 1997-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2250067-A1 |
| titleOfInvention | In vitro fluorescence polarization assay |
| abstract | An in vitro assay method permits the identification of a test substance which inhibits the mutual association of a pair of proteins. The method includes the steps of providing a pair of proteins capable of mutual association, one of said proteins bearing a covalently linked fluorophore; preparing a mixture containing the two proteins and at least one test substance; irradiating the mixture with polarized light of a suitable wavelength permitting excitation of the fluorophore as indicated by emission of polarized light; measuring the degree of polarization of the emission, and determining the effect of the presence or concentration of the test substance in decreasing the observed emission polarization of a mixture of the two proteins alone. Inhibitory activity of in the test substance correlates with decreased depolarization values. |
| priorityDate | 1996-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 185.