| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97ddd4d1d0ebc8a7d2c8e7d214d08cf3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
| filingDate |
1997-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2007-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8d4ba02d0b049204b063c003bace326
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_817cce9004ccf1c3993834912a80c968
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94c8110884aeb13fe839309e904be080
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a8b52bb580eb7cc60b4f6300dfb4e31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_754f6b6d18b4e636853cde046af29d0c |
| publicationDate |
2007-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2247328-C |
| titleOfInvention |
Neuropeptides originating in scorpion |
| abstract |
The invention provides a peptide capable of blocking voltage-gated K+ channels and inhibiting IL-2 production, which is represented by an amino acid sequence of: Ala-Ser-Cys-Arg-Thr-Pro-Lys-Asp-Cys-Ala-Asp-Pro-Cys-Arg-Lys- Glu-Thr-Gly-Cys-Pro-Tyr-Gly-Lys-Cys-Met-Asn-Arg-Lys-Cys-Lys-Cys-Asn-Arg-Cy s; in which the C-terminal is amidated and four disulfide bridges are present in the molecule, and their related peptides isolated from the venom gland of a scorpion Heterometrus spinnifer. The peptides provided by the present invention are neuropeptides which can block voltage-gated K+ channels and inhibit IL-2 production at an extremely low concentration and, therefore, are expected to contribute to application of scorpion toxins to medicines and so on. |
| priorityDate |
1996-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |