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filingDate 1996-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9178a85ace424f4b1e13ab030bbb1fc
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publicationDate 1997-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2246561-A1
titleOfInvention Modulators of expression and function of lrp in alzheimer's disease
abstract The present invention broadly relates to the treatment, diagnosis, and prophylactic prevention of Alzheimer's disease. More specifically, the present invention relates to methods and compositions for preventing the endocytosis and cellular internalization of integral membrane amyloid .beta.-precursor protein (APP) and its subsequent catabolism by blocking or interfering with the association or binding of APP with members of the low density lipoprotein receptor family._________________________________________________
priorityDate 1995-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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