http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2244870-A1

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filingDate 1997-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_715bf9b52e236d5d66cec00357565b85
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publicationDate 1997-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2244870-A1
titleOfInvention N,n-disubstituted amic acid derivatives
abstract A compound represented by general formula (I) or a pharmaceutically acceptable salt or ester thereof: (see formula I) [wherein each of Ar1, Ar2, Ar3 and Ar4 is an aryl group or an aromatic heterocyclic group; A1 is a C2-6 chain hydrocarbon group or a group represented by -A1a-W1-A1b-(wherein W1 is an oxygen atom, a sulfur atom, an ethynylene group, a cyclopropylene group or a group represented by -NR W-; A2 is a C2-8 chain hydrocarbon group; each of X and Y is an oxygen atom, a sulfur atom, a carbonyl group or a group represented by -CHR a- or by -NR b-, or X and Y together represent a vinylene group or an ethynyl ene group; each of R1, R2, R3, R7 and R8 is a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group, a lower alkenyl group or a lower alkoxy group; each of R4 and R5 is a hydrogen atom, a halogen atom, a hydroxyl group, an amino group, a nitro group, a cyano group, a carboxyl group, a lower alkoxycarbonyl group, a carbamoyl group, a lower alkylcarbamoyl group, a lower alkyl group, a lower hydroxyalkyl group, a lower fluoroalkyl group or a lower alkoxy group; and R6 is a lower alkyl group, provided that when one of X and Y is an oxygen atom, a sulfur atom or a group represented by -NR b-, the other is a carbonyl group or a group represented by -CHR a- and an antitumor agent comprising it as an active ingredient.
priorityDate 1996-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 34.