| abstract |
A combinatorial library is disclosed which is represented by formula (I) or (I') wherein: (A) is a solid support; T'-L- is an identifier residue; and -L'-II' is a ligand/linker residue. This library contains hydroxypropylamines of the formula (II): -Aa1-Aa2-(CH2Ar1)-CH2CHOH-CH2XR1 wherein: Aa1 and Aa2 is each an amino acid joined to each other through an amide bond; Ar1 is an aromatic ring system; -CH2Ar1 is attached to N on Aa2; and R1 is H, C1-20 alkyl, alkenyl, alkynyl, aryl, heteroaryl, aryl or heteroaryl fused to a 3- or 4-membered moiety to form a non-aromatic second ring, or substituted C1-20 alkyl, alkenyl, or alkynyl. |