| abstract |
A method of treating a disorder characterized by the overexpression of deaminase or deoxycytidine deaminase in a subject in need of such treatment is disclosed. The method comprises administering a compound of Formula (I) wherein X and X1 are each independently C or N; R1 is lower alkyl, lower alkenyl, lower alkynyl, halogen, or haloalkyl; and R2 is H, -N3, -OH, amino, or halogen; or a pharmaceutically acceptable salt thereof, to the subject in an amount effective to treat the disorder. Pharmaceutical formulations useful in the method of the present invention are also disclosed. |