http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2239733-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d55444126b55e1edeb40523a4818da76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1782fde68e8711188a1881f5284fe0b0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8163fbef2af3517f15697457ea2eb280 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-828 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08 |
| filingDate | 1996-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2001-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9e755ddf96de18d08ecfb573c63e525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efbe0aab8c4168b27c083fe58e53132f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27fa01fe8d8a771396db7b706f849e5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f0a4a389a92a7757b6877eb19ddaa3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e66a55ab9576ad762653d5764d346928 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_678780ab68a173a965728760692e31f1 |
| publicationDate | 2001-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2239733-C |
| titleOfInvention | Chromosome 13-linked breast cancer susceptibility gene |
| abstract | The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human breast cancer predisposing gene (BRCA2), some mutant alleles of which cause susceptibility to cancer, in particular breast cancer. More specifically, the invention relates to germline mutations in the BRCA2 gene and their use in the diagnosis of predisposition to breast cancer. The present invention further relates to somatic mutations in the BRCA2 gene in human breast cancer and their use in the diagnosis and prognosis of human breast cancer. Additionally, the invention relates to somatic mutations in the BRCA2 gene in other human cancers and their use in the diagnosis and prognosis of human cancers. The invention also relates to the therapy of human cancers which have a mutation in the BRCA2 gene, including gene therapy, protein replacement therapy and protein mimetics. The invention further relates to the screening of drugs for cancer therapy. Finally, the invention relates to the screening of the BRCA2 gene for mutations, which are useful for diagnosing the predisposition to breast cancer. |
| priorityDate | 1995-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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