abstract |
Drugs having an inhibitory activity on thymidine phosphorylases and inhibiting cancerous metastasis, which contain as the active ingredient uracil derivatives represented by general formula (1) or salts thereof, wherein R1 represents chlorine, bromine, iodine, cyano or lower alkyl; and R2 represents an optionally substituted 4- to 8-membered heterocycle having nitrogen, optionally substituted amidinothio, guanidino, lower alkylamidino, amino, etc. |