abstract |
A method of inhibiting plasminogen activator inhibitor 1 comprising administering to a human in need thereof an effective amount of a compound having formula (I), wherein R1 and R3 are independently hydrogen, -CH3, (a) or (b), wherein Ar is optionally s ubstituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt or solvate thereof. |