| abstract |
Compounds of the formulae (see formula I) R1 R2 R3,R3' R4 R5 R6 evernino micrin H OH OH,H OMe Cl Me Compd A CI OH OH,H OMe Cl Me Compd B H OH =O OMe Cl Me Compd D H OMe OH,H OMe Cl Me Compd E H OH OH,H OH H Me Compd F H OH OH,H OMe H Me Compd G H OH OH,H OMe Cl H; or <IMGS> wherein R7=CH3; R8=CH3; (Compound C) or R7=C(O)H; R8 =H (Compound H), or and pharmaceutically acceptable salts thereof, or orthosomycins which have been isolated from the fermentation broth of the microorganism Micromonospora Carbonacea var Africano designated SCC 2146, these compounds are antibacterial agents useful in treating bacterial infections.< /SDOAB> |