Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7115ef17a0cce55f36229865e31ea6a0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-183 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-186 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 |
filingDate |
1997-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2006-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b4d5c9e060e45317c62038360f6311d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1afb1e67a23c496f6be6a4d773e1a4e |
publicationDate |
2006-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2232435-C |
titleOfInvention |
Preservative systems for pharmaceutical compositions containing cyclodextrins |
abstract |
Disclosed are preservative systems useful in aqueous pharmaceutical compositions containing an active agent and a cyclodextrin. The preservative systems comprise boric acid and one or more compounds selected from the group consisting of C16 benzalkonium halide compounds, polymeric quaternary ammonium compounds, and quaternary ammonium alkylene glycol phospholipid derivatives of structure (I), where a + b = 3; R1 is C8-C22 alkyl or alkene; X is NH, O or CH2; R2 is C2-C6 alkyl; each R3 is independently C1-C12 alkyl or alkene; and Y is nothing or C1-C6 alkyl or alkene; and pharmaceutically acceptable salts thereof. |
priorityDate |
1996-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |