abstract |
2-Acylbenzamide derivatives represented by general formula (I), (wherein R1, R2, R3, R4 and R5 represent each hydrogen, etc.; X represents vinylene, etc.; and B represents -N(R6) (R7) (wherein R6 and R7 represent each hydrogen, etc.), -NH-(CH2)n-A-R8 (wherein A represents a single bond, etc.; and R8 represents hydroxy, etc.) or hydroxyamino, which is useful as a preventive and remedy for diseases caused by the supermultiplication of vascular intimal cells. |