http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2230960-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbb7e0584e2cd03abf527efa781deff2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate | 1997-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eee6e255783c8deb86bdfc46d7f2c6b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9d2f350f67adb79aaa73d4d22ae83d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1abdde2de687d31a369bd50676be930 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc641e554b7f2c9f03facc8bad4a04bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_672ada4aa923e5fa41ee11ea2a8e9056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c98db5051512b115aa2cc973654275c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17dbf78eaeb0b0a43782b6f033e66e00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec309a2b7031e22cb927a68afaf7ab8c |
| publicationDate | 2007-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2230960-C |
| titleOfInvention | Piperazine derivatives and process for the preparation thereof |
| abstract | The present invention relates to new piperazine derivatives having the general formula (I): wherein R1 or a R2 are the same or different or a each represent a hydrogen atom, a substituted or unsub-stituted C1-C8 alkyl group, a substituted or unsub-stituted C3-C6 cycloalkyl group, a substituted or unsubstituted C2-C8 unsaturated alkyl. group, a ketone group, a substituted or unsubstituted aryl group, a substituted or unsubstituted C1-C4 alkoxy group, a substituted or unsubstituted arylhydroxy group, a substituted or unsubstituted amino group, a C1-C4 ester group, a C1-C4 thioester group, a thiol group, a substituted or unsubstituted carboxyl. group, an epoxy group, or a substituted or unsubstituted C1-C4 thio-alkoxy group, or R1 or a R2 are fused to form a C3-C4 saturated or unsaturated chain; R3, R4, R5, R6 or a R7 are the same or different or a each represent a hydrogen atom, a halogen atom, a hydroxy group, a nitro group, a C1-C4 ester group, a lower alkyl group, a C1-C4 thio-alkyl group, a substituted or unsubstituted C3-C6 cycloalkyl group, a lower alkoxy group, a C1-C4 thioalkoxy group, a substituted or unsubstituted aryl group, a substituted or unsubstituted lower arylalkoxy group, a substituted or unsubstituted lower alkylamino group, or a lower alkyl substituted or unsubstituted carbamate group; or two adjacent groups among R3, R4, R5, R6 or a R7 are bonded with each other to form a 1,2-phenylene or 2,3-naphthylene group; X is an oxygen or sulfur atom, or a substituted or unsubstituted imino group; Y is bonded at the 3-position or 4-position of the aromatic ring or a represents an oxygen atom or -NR8- in which R8 has the same meaning as R3; Z is a hydroxy group, a lower alkoxy group, a C1-C4 thioalkoxy group, a substituted or unsubstituted aryloxy group, a lower alkylamino group, or a substituted or unsubsti-tuted cycloamino containing 1-5 nitrogen atoms; A is a nitrogen atom or -CH=; or a their pharmaceutically acceptable acid addition salt. The compounds of formula (i) are useful for the prevention or treatment of tumors in mammals. |
| priorityDate | 1996-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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