http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2230753-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f5c494c7664892b6f9c759b0e9e3f55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6841 |
| filingDate | 1996-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15d622515120cdc167b7b4c4c27b33cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ade4f2ad56f14ae4fe41a63ec60aaa21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e82c3797be1fee2ee69340e2bb6cf2b9 |
| publicationDate | 1997-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2230753-A1 |
| titleOfInvention | Methods for labeling dna ends with halogenated nucleotides and detecting same with antibodies |
| abstract | The invention pertains to the field of DNA detection for basic research, medical diagnostic testing, and forensic testing. Methods are provided for the end labeling of DNA strands. The DNA strands are first incubated with a halogenated deoxynucleotide triphosphate, such as brominated deoxyuridine triphosphate (BrdUTP), and an enzyme which can catalyze the addition of the halogenated deoxynucleotide to the 3'OH ends of the DNA strand, such as terminal deoxynucleotide transferase (TdT). The resulting modified DNA strands are then incubated with a labeled antibody, such as a fluoresceinated monoclonal antibody, that specifically binds to the halogenated deoxynucleotide. The label is then detected, e.g., by flow cytometry. The methods have utility in detecting apoptosis, in detecting DNA synthesis and/or repair, and as general methods for end labeling of DNA. |
| priorityDate | 1995-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 101.