http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2229470-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_562f0151e55dd3b1ab0bc517e35b18c9 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-267 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-46 |
| filingDate | 1997-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f69a5117cf5f038722752bb130e887b5 |
| publicationDate | 2006-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2229470-C |
| titleOfInvention | Process for the purification of an intermediate in the preparation of iopamidol |
| abstract | This invention refers to a new process for the synthesis of (S)-N,N'-bis[(2-hydroxy-1-(hydroxy-methyl)ethyl]-5-[(2-hydroxy-1-oxopropyl]amino]-2,4,6-triiodo-1,3-benzendicarboxamide, of formula (III), starting from 5-amino-2,4,6-triiodo-1,3-benzendicarboxylic acid dichloride characterized by a new step of chromatographic purification through resins of (S)-5-[[2-(acetyloxy)-1-oxopropyl]amino]-2,4,6-triiodo-1,3-benzendicarboxylic acid dichloride, which enables the direct conversion to the compound of formula (III), without preventive isolation. |
| priorityDate | 1996-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.