http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2221278-C

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-62
filingDate 1996-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2008-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b7d9e90498dff0425152759aac535cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c103fa5eff2b644a54bdad9abfb31818
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28e562cd29063502f67e9df264fb3d56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b132f8cd18b9ef316edd9305a9469ab
publicationDate 2008-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2221278-C
titleOfInvention Process for the preparation of 5-amino-2,4,6-triiodoisophthalic acid dichloride by chlorination with thionyl chloride in the presence of a catalyst
abstract A process for the preparation of 5-amino-2,4,6-triiodoisophthalic acid dichloride by chlorination of 5-amino-2,4,6-triiodoisophthalic acid with thionyl chloride in the presence of a suitable solvent characteriz ed in that the reaction is carried out in the presence of catalytic amounts of a tetraalkylammonium salt of the formula (I): R1R2R3R4NX wherein X is halogen, mesylate or tosylate; R1, R2, R3 and R4, the same or different, are C1-C20 alkyl groups so that the total number of carbo n atoms of the groups R1, R2, R3 and R4 is higher than 16. The 5-amino-2,4,6-triiodoisophthalic acid dichloride obtained according to the process of the present invention is useful as intermediate in the synthesis of iodinated contrast media.
priorityDate 1995-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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