http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2221278-C
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7fe151308388476e056181c18272ea4 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-62 |
filingDate | 1996-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2008-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b7d9e90498dff0425152759aac535cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c103fa5eff2b644a54bdad9abfb31818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28e562cd29063502f67e9df264fb3d56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b132f8cd18b9ef316edd9305a9469ab |
publicationDate | 2008-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2221278-C |
titleOfInvention | Process for the preparation of 5-amino-2,4,6-triiodoisophthalic acid dichloride by chlorination with thionyl chloride in the presence of a catalyst |
abstract | A process for the preparation of 5-amino-2,4,6-triiodoisophthalic acid dichloride by chlorination of 5-amino-2,4,6-triiodoisophthalic acid with thionyl chloride in the presence of a suitable solvent characteriz ed in that the reaction is carried out in the presence of catalytic amounts of a tetraalkylammonium salt of the formula (I): R1R2R3R4NX wherein X is halogen, mesylate or tosylate; R1, R2, R3 and R4, the same or different, are C1-C20 alkyl groups so that the total number of carbo n atoms of the groups R1, R2, R3 and R4 is higher than 16. The 5-amino-2,4,6-triiodoisophthalic acid dichloride obtained according to the process of the present invention is useful as intermediate in the synthesis of iodinated contrast media. |
priorityDate | 1995-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.