http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2217849-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0be8d6cfb14d04522568dd6146ad713a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 |
| filingDate | 1996-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2007-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e09c7d55446c47f338b502233a094081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52336e4450891e248a503f629ce9eee3 |
| publicationDate | 2007-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2217849-C |
| titleOfInvention | A process for the preparation of lercanidipine hydrochloride |
| abstract | A process for the preparation of methyl 1,1,N-trimethyl-N-(3,3-diphenyl-propyl)-2-aminoethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylate (lercanidipine) of formula I comprises reacting an acid halide of 2,6-dimethyl-5-methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid with 2,N-dimethyl-N-(3,3-diphenylpropyl)-1-amino-2-propanol in an aprotic solvent. The product can be isolated by industrially applicable crystallization techniques and is obtained in high yield as its anhydrous hydrochloride, a form which possesses high stability and low hygroscopicity. |
| priorityDate | 1995-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.