http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2217821-C
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 |
| filingDate | 1996-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a4d7b76d854221991fc40b7a58f2494 |
| publicationDate | 2008-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2217821-C |
| titleOfInvention | Benzopyrans and pharmaceutical compositions containing them |
| abstract | The invention provides a compound of formula I wherein R1 is a mono- or bicyclic aromatic group optionally containing one or more nitrogen atoms and optionally substituted with up to three substituents selected from halogen, C1-5alkyl, (halo)1-3-C1-5alkyl or C1-5alkoxy, R2 is H or C1-5alkyl, or is C2.5alkylene linked to R1, R3 is a group of formula -N(R9)-COR10 wherein R9 is hydrogen and R10 is phenyl or pyridyl, or R9 and R10 together are 1,3-butadienylene or represent a group of formula -(CH2)n- or in which n is an integer of from 3 to 5 inclusive and m is 1 or 2, R4 is hydrogen and R5 is hydroxy in the trans position with respect to R3, R6 and R7 are, independently, C1-5alkyl, and R8 is hydrogen or C1-5alkyl; or N-oxide thereof; or physiologically-hydrolysable and -acceptable ester of such a compound or N-oxide, or acid addition or quaternary ammonium salt of such a compound, N-oxide or ester. The invention also provides processes for their production; and their uses as pharmaceuticals, e.g. as K+ -channel openers, bronchodilators and agents for the suppression of airways hyperreactivity, e.g., for use in the treatment of asthma. |
| priorityDate | 1995-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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