http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2217226-A1

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filingDate 1996-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a8dac62e1b5ce318f600168dab1b2a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bf32192e29c78e716b3a3a7f716587c
publicationDate 1996-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2217226-A1
titleOfInvention Controlled release formulation for water soluble drugs in which a passageway is formed in situ
abstract A controlled release pharmaceutical tablet is disclosed which is based on: (a) a compressed core which contains: i) a medicament; ii) from 5 to 20 % by weight of a water soluble osmotic agent based on the total weight of the compressed core; iii) a water soluble pharmaceutically acceptable polymeric binder; iv) a conventional pharmaceutical excipient; and (b) a dual layer membrane coating around said core which consists essentially of: i) a first inner coating layer for sustained release of the medicament, said inner coating layer consisting essentially of a plasticized water insoluble pharmaceutically acceptable polymer and a pharmaceutically acceptable water soluble polymer, and; ii) a second outer coating layer for immediate release of a medicament, said outer coating layer consisting essentially of an effective amount of a medicament and a water soluble polymer. The controlled release formulation is suitable for the once-a-day administration of medicaments.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6171618-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6537573-B2
priorityDate 1995-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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