| abstract |
Process for the preparation of streptogramins of general formula (I) in which either R1 is methyl or ethyl, R2 is H and X and Y form together an oxo radical, either R1 is ethyl, R2 and X represent H and Y is H or OH, either R1 is ethyl R2 is OH and X and Y together form an oxo radical, by demethylation of a synergistin derivative of general formula (II) in which R1, R2, X and Y are defined as above, by treatment with a periodate in acetic medium followed by treatment in aqueous medium. |