| abstract |
A method of inhibiting 5-lipoxygenase comprising administering to a mammal in need thereof an effective amount of a compound having formula (I), wherein R1 and R2 are independently hydrogen or C1-C6 alkyl; R3 is hydrogen, or a group of formula (a), wherein R4 is phenyl, substituted phenyl, naphthyl or substituted naphthyl, with the proviso that when R1 and R2 are both C1-C6 alkyl, R3 is not hydrogen; and pharmaceutically acceptable salts thereof. |