http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2214393-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-16 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-16 |
filingDate | 1997-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9037d03b1fd3b7eeda4aebb973c21d0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cfe63601d74bad7cabd11271e1343cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26506fcadaab848710cf3cda565bc9b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86d3ed42917cc399ffcd67f32b572fa4 |
publicationDate | 1998-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2214393-A1 |
titleOfInvention | Tricyclic compounds, their production and use |
abstract | ABSTRACT A pharmaceutical composition for treating or preventing proliferative glomerulonephritis, which comprises a compound of the formula: (see fig.I) wherein ring A is a nitrogen-containing heterocyclic ring, having two nitrogen atoms as the hetero-atoms, which may be substituted with oxo or thioxo; ring Q may be substituted; Y is an optionally substituted hydrocarbon group, an optionally substituted hydroxy group or an optionally substituted mercapto group; and Rl is a hydrogen atom, a halogen atom, an optionally substituted hydrocarbon group or an acyl group, or a salt thereof, and a novel compound of the formula: (see fig.II) wherein ring Aa may have one oxo group; D is a bond or an optionally substituted divalent hydrocarbon group; ring W is an optionally substituted nitrogen-containing heterocyclic ring; ring Q may be substituted; and R3 is an electron-withdrawing group, or a salt thereof, which have excellent PDGF-inhibiting activities, activities of ameliorating renal diseases and activities of lowering lipid level and are less toxic and are useful as a preventive and treating agent for cardisvascular diseases. |
priorityDate | 1996-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 371.