http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2211414-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_634715a790f7ef0163a61e9f364bebcd |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-15 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
filingDate | 1996-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be61c83f813d3dc8bcd538ec98766552 |
publicationDate | 1996-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2211414-A1 |
titleOfInvention | Methods for testing of therapeutic compounds |
abstract | The present invention is related to a method for determining the efficacy of a chemical compound for treatment of recurrent herpes virus infection, said method comprising: (a) inoculating herpes virus at a primary skin site of a non-human mammal to cause zosteriform spread of the virus through nerve cells to cause lesions at a secondary (distal) site of infection; (b) before the appearance of skin lesions at the secondary site caused by the virus, giving adoptive transfer of immunity (ATI) to the said non-human mammal, so as to provide immunity mimicking the immunological reactivity seen in a recurrent herpes virus infection in a previously infected immune host; (c) administering a chemical compound to be tested to the said non-human mammal; and (d) determining the ability of the said chemical compound to reduce the occurrence and/or severity of herpes virus-induced skin lesions at the secondary site of infection. |
priorityDate | 1995-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.