Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_280d87031f0c5786de1808713a1b76b7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
1995-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2001-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e892562b674a96b4d2132b4cec32567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81cfb8613085f631e4004dcc3c762038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5609ca6db3717ca813bcf2a0f51aed2f |
publicationDate |
2001-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2203689-C |
titleOfInvention |
Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides |
abstract |
The synthesis and elucidation of nineteen heterocyclic or halophenyl amide derivatives of dolastatin (10) are disclosed. These compounds and the method s of producing those compounds offer demonstrated significant in vitro activit y against several human cancer cell lines. These compounds and the methods of producing those compounds offer a commercially viable alternative to natural and synthetic dolastatin (10). |
priorityDate |
1994-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |