http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2200578-A1

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filingDate 1995-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_213c28e1175caf46713d15a6316a2d87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fb82354f170ed7f3cf80304eb7fcc6d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5adc67e1c0c8ef0529654e3966664a80
publicationDate 1996-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2200578-A1
titleOfInvention N-substituted piperidinyl bicyclic benzoate derivatives
abstract The present invention is concerned with novel benzoate derivatives laving formula (I), the N-oxide forms, the salts and the stereochemically isomeric forms thereof, wherein: R1 is halo or C1-6alkylsulfonylamino; A represents a bivalent radical of formula -CH2-CH2- (a), -CH2CH2-CH2-(b), -CH-CH- (c), in the radicals (a), (b) and (c) one or two hydrogen atoms may be replaced by a C1-6alkyl; R2 is hydrogen or C1-6alkyloxy; L is a radical of formula: -Alk-R4 (d), -Alk-O-R5 (e) -Alk-NR6R7 (f), Alk is C1-12alkanediyl; R4 is hydrogen; cyano; C1-6alkylcarbonyl; C1-6alkyloxycarbonyl; C3-7cycloalkyl; C1-6alkylsulfinyl; C1-6alkylsulfonyl; phenyl or phenyl substituted with halo, C1-6alkyl or C1-6alkyloxy; tetrahydrofuran; dioxolane; dioxolane substituted with C1-6alkyl; dioxane; dioxane substituted with C1-6alkyl; pyridine; pyridine substituted with halo or C1-6alkyl; pyridazine; pyridazine substituted with one or two substituents selected from halo, C1-6alkyl, hydroxy or an optionally substituted benzimidazolone or an optionally substituted imidazolone; R5 is hydrogen; C1-6alkyl; hydroxyC1-6alkyl; C1-6alkylcarbonyl; phenyl or phenyl substituted with up to three substituents selected from halo, C1-6alkyl, C1-6alkyloxy; R6 is hydrogen or C1-6alkyl; R7 is hydrogen; C1-6alkyl; C1-6alkylcarbonyl; C1-6alkyloxycarbonyl; pyridazine; pyridazine substituted with one or two substituents selected from halo, C1-6alkyl, hydroxy; pyrazine; pyrazine substituted with one or two substituents selected from halo, C1-6alkyl, hydroxy. Pharmaceutical compositions comprising said compounds, processes for preparing compounds and compositions as well as the use as a medicine, in particular for the treatment of gastrointestinal disorders involving a decreased colon motility are described.
priorityDate 1994-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 49.