http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2195217-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0157717feee65f44161decc7e5cf0099 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56972 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 1995-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8afe6be4bbaa43e45b2006a31cef455b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c79952a849f822c23a62e2b28de70315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cc0ba713f5ecbe9422437b87057e606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09d5f44fa5564e6f52d8427650c24eb5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01dd8894eb2e8ec2bda8747ae325f1f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8356f2c9882932848553dc5be96e3482 |
publicationDate | 1996-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2195217-A1 |
titleOfInvention | Methods of identifying patients having an altered immune status |
abstract | Methods of identifying a patient having an altered immune status involve determining an immune status index for the patient and comparing it to the immune status index in healthy individuals. In general, an immune status index is the ratio of the amount of a protein that varies significantly in a patient with an altered immune status to the amount of another protein that is substantially invariant in both healthy and immune-altered individuals. Variable proteins can be TCR subunit proteins, T lymphocyte signal transduction pathway proteins, polynucleotide binding proteins or biological response modifiers (BRM). In addition, the ratio of a TH-1-type BRM to a TH-2-type BRM, the ratio of cytoplasmic to nuclear levels of polynucleotide binding proteins, the pattern of protein binding to an oligonucleotide probe that comprises the protein binding region of a gene for a BRM, or the pattern of distribution of T lymphocytes in a density gradient following density gradient centrifugation are also suitable as an immune status index. The methods are useful in identifying patients exhibiting immunosuppression, hyperimmunity and autoimmunity, as well as in assessing the immune status of a patient undergoing organ transplant. |
priorityDate | 1994-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 303.